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The No. 21 Iowa State Cyclones kick off their 2025 season against the Big 12 Conference rival Kansas State Wildcats in a Week 0 matchup in Ireland on Saturday. Iowa State shared the regular-season Big 12 championship, while Kansas State shared eighth-place in the conference with West Virginia. The Wildcats (5-4, 9-4), who were 2-1 against ranked opponents a year ago, had a plus-97 point differential. The Cyclones (11-3, 7-2), who were 9-2 against unranked foes, were plus-114 in point differential.
Kickoff is set for noon ET at Aviva Stadium in Dublin. Iowa State leads the all-time series 54-50-4, including a 29-21 win last season. The Wildcats are 3-point favorites in the latest Iowa State vs. Kansas State odds, while the over/under for total points scored is 50.5. Before making any Iowa State vs. Kansas State picks, be sure to see what SportsLine expert Josh Nagel has to say. New users can also target the DraftKings promo code, which offers $200 in bonus bets instantly plus over $200 off NFL Sunday Ticket:
Josh Nagel is SportsLine’s assistant managing editor and has covered the wagering industry on a variety of platforms for decades, and has won numerous sports handicapping contests. He has also had success in his college football picks, including going 8-0 (+850) in his last eight Kansas State picks.
Now, Nagel has set his sights on Iowa State vs. Kansas State and just locked in his picks and college football predictions. You can head to SportsLine now to see his picks. Here are several college football odds and betting lines for Iowa State vs. Kansas State:
Iowa State vs. Kansas State spread
Kansas State -3 at DraftKings Sportsbook
Iowa State vs. Kansas State over/under
50.5 points
Iowa State vs. Kansas State money line
Iowa State +134, Kansas State -160
Iowa…
Source link : https://www.cbssports.com/college-football/news/kansas-state-vs-iowa-state-prediction-odds-time-2025-dublin-college-football-picks-from-expert-on-8-0-run/
Author : Daniel Kohn
Publish date : 2025-08-22 16:08:00
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